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ey0017.11-12 | Pharmacologic Treatment | ESPEYB17

11.12. A randomized, controlled trial of liraglutide for adolescents with obesity

AS Kelly , P Auerbach , M Barrientos-Perez , I Gies , PM Hale , C Marcus , LD Mastrandrea , N Prabhu , S; NN8022-4180 Trial Investigators Arslanian

To read the full abstract: N Engl J Med. 2020;382(22):21172128. doi: https://pubmed.ncbi.nlm.nih.gov/32233338/Kelly et al. randomly assigned (1:1) n =251 obese adolescents (age 12 to <18 years) to receive either liraglutide (3.0 mg), a long-acting glucagon-like peptide-1 agonist, or placebo subcutaneously once daily in addition to lifestyle therapy. Liraglutide w...

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ey0017.11-15 | New Insight into Bariatric Surgery | ESPEYB17

11.15. 5-year mental health and eating pattern outcomes following bariatric surgery in adolescents: a prospective cohort study

Jarvholm , G Bruze , M Peltonen , C Marcus , CE Flodmark , P Henfridsson , AJ Beamish , E Gronowitz , J Dahlgren , J Karlsson , T Olbers

To read the full abstract: Lancet Child Adolesc Health. 2020;4(3):21019. PMID 31978372.In this non-randomized matched-control study, 81 obese adolescents undergoing Roux-en-Y gastric bypass surgery (RYGB) who participated in the Adolescent Morbid Obesity Surgery (AMOS) study (11) were compared with 80 obese controls from the Swedish Childhood Obesity Treatment Register (BORIS) who rec...

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ey0018.10-8 | (1) | ESPEYB18

10.8. Absence of islet autoantibodies and modestly raised glucose values at diabetes diagnosis should Lead to testing for MODY: lessons from a 5-year pediatric Swedish National Cohort study

A Carlsson , M Shepherd , S Ellard , M Weedon , A Lernmark , G Forsander , K Colclough , Q Brahimi , C Valtonen-Andre , SA Ivarsson , H Elding Larsson , U Samuelsson , E Ortqvist , L Groop , J Ludvigsson , C Marcus , AT Hattersley

Diabetes Care. 2020; 43:8289. doi: 10.2337/dc19-0747.It is often difficult to identify maturity-onset diabetes of the young (MODY) in pediatric patients close to diabetes onset. Hence, misdiagnosis and unnecessary insulin treatment are still common.This study reports the discriminatory clinical features at diabetes onset in Swedish pediatric patients (age 118 y...

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ESPE Yearbook of Paediatric Endocrinology

11.12. A randomized, controlled trial of liraglutide for adolescents with obesity

11.15. 5-year mental health and eating pattern outcomes following bariatric surgery in adolescents: a prospective cohort study

10.8. Absence of islet autoantibodies and modestly raised glucose values at diabetes diagnosis should Lead to testing for MODY: lessons from a 5-year pediatric Swedish National Cohort study

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